Malignant phaeochromocytoma and hypercalcaemia.
نویسندگان
چکیده
We describe a case of hypercalcaemia secondary to recurrent malignant phaeochromocytoma. Parathyroid-related protein (PTHrp 1-86) immunoreactivity was identified in plasma and PTHrp was identified by immunocytochemistry in tumour tissue.
منابع مشابه
Hypercalcaemia and phaeochromocytoma.
A patient with a phaeochromocytoma associated with hypercalcemia is described. The hypercalcaemia was corrected by removal of the phaeochromocytoma. Parathyroid hormone-like peptide was isolated from the tumour suggesting that ectopic parathyroid hormone production from the phaeochromocytoma was the explanation of the hypercalcaemia.
متن کاملPhaeochromocytoma and hypercalcaemia.
Introduction Phaeochromocytoma may occasionally induce hypercalcaemia. Case reports of correction of hypercalcaemia by surgical removal of the phaeochromocytoma indicate the importance of humoral mechanisms (Swinton, Clerkin and Flint, 1972; Kukreja et al., 1973). Kukreja et al. (1973) noted a pre-operative elevation of serum immuno-reactive parathyroid hormone (i-PTH) implying that hypercalcae...
متن کاملScalp metastasis in a patient with phaeochromocytoma.
Phaeochromocytomas are catecholamine secreting tumours arising from chromaffin cells of the adrenal medulla [1]. 10% of the tumours are bilateral and 10% are malignant. Malignant tumours most commonly metastasise to lungs, bone, liver or lymph nodes or may recur locally [1]. Surgical resection is the treatment of choice followed by adjuvant combined chemotherapy [1]. Five year survival rate for...
متن کاملMechanism of malignant hypercalcaemia in carcinoma of the breast.
To investigate the mechanisms of hypercalcaemia in carcinoma of the breast, 22 patients with hypercalcaemia due to metastatic carcinoma were studied and the findings compared with those obtained in normal subjects and patients with benign and malignant breast disease without hypercalcaemia. As expected, patients with metastases of bone showed biochemical evidence of increased bone resorption. W...
متن کاملDrugs for the treatment of hypercalcaemia
Hypercalcaemia is ordinarily treated by treatment of the underlying disorder. In some cases, as in malignant disease, in vitamin D poisoning and after a failed parathyroidectomy, the hypercalcaemia itself needs to be treated. A large number of methods have been advocated for this, but phosphate is the drug of choice in most patients. This paper outlines its use, mode of action and side effects ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 69 807 شماره
صفحات -
تاریخ انتشار 1993